Browsing by Author "Dardiotis, Efthymios"

Now showing items 1-5 of 5

    • Article  

      Complement C1Q polymorphisms modulate onset in familial amyloidotic polyneuropathy TTR Val30Met 

      Dardiotis, Efthymios; Koutsou, Pantelitsa; Zamba-Papanicolaou, Eleni; Vonta, Filia; Hadjivassiliou, Marilena; Hadjigeorgiou, Georgios M.; Cariolou, Marios A.; Christodoulou, Kyproula; Kyriakides, Theodoros (2009)
      Background: Familial amyloidotic polyneuropathy (FAP) TTR Val30Met is a lethal autosomal dominant sensorimotor and autonomic neuropathy due to a substitution of methionine for valine at position 30 of the transthyretin ...
    • Article  

      A correlative study of quantitative EMG and biopsy findings in 31 patients with myopathies 

      Dardiotis, Efthymios; Papathanasiou, Eleftherios Stelios; Vonta, Filia; Hadjigeorgiou, Georgios M.; Zamba-Papanicolaou, Eleni; Kyriakides, Theodoros (2011)
      A direct correlation of QEMG with muscle biopsy findings might help delineate the sensitivity of QEMG in identifying muscle pathology as well as provide information on electrophysiological-histological correlations. In a ...
    • Article  

      Epidemiological, clinical and genetic study of familial amyloidotic polyneuropathy in Cyprus 

      Dardiotis, Efthymios; Koutsou, Pantelitsa; Papanicolaou, Eleni Zamba; Vonta, Filia; Kladi, Angelica; Vassilopoulos, Dimitrios C.; Hadjigeorgiou, Georgios M.; Christodoulou, Kyproula; Kyriakides, Theodoros (2009)
      Objectives. To define the incidence and prevalence of familial amyloidotic polyneuropathy (FAP) TTRVal30Met on the island of Cyprus. To study the clinical phenotype and genetic features of FAP TTRVal30Met in the Cypriot ...
    • Article  

      Intraperitoneal melatonin is not neuroprotective in the G93ASOD1 transgenic mouse model of familial ALS and may exacerbate neurodegeneration 

      Dardiotis, Efthymios; Panayiotou, Elena; Feldman, M. L.; Hadjisavvas, Andreas; Malas, Stavros; Vonta, Filia; Hadjigeorgiou, Georgios M.; Kyriakou, Kyriakos; Kyriakides, Theodoros (2013)
      In amyotrophic lateral sclerosis (ALS) reactive oxygen species and apoptosis are implicated in disease pathogenesis. Melatonin with its anti-oxidant and anti-apoptotic properties is expected to ameliorate disease phenotype. ...
    • Article  

      Regulatory B and T lymphocytes in multiple sclerosis: friends or foes? 

      Vasileiadis, Georgios K.; Dardiotis, Efthymios; Mavropoulos, Athanasios; Tsouris, Zisis; Tsimourtou, Vana; Bogdanos, Dimitrios P.; Sakkas, Lazaros I.; Hadjigeorgiou, Georgios M. (2018)
      Current clinical experience with immunomodulatory agents and monoclonal antibodies in principle has established the benefit of depleting lymphocytic populations in relapsing–remitting multiple sclerosis (RRMS). B and T ...